6 Desktop Essential AppsShowing apps #1 - 20. 
TweetDeck
TweetDeck is your personal browser for staying in touch with what’s happening now, connecting you with your contacts across Twitter, Facebook and more. TweetDeck shows you everything you want to see at once, so you can stay organised and up to date.
Tweetie for Mac
Tweetie for Mac is a desktop rewrite of the original Tweetie client. Tweetie is free to download and try for as long as you want. It's full-featured and has some of the most beautiful ads around (courtesy of Fusion Ads). You can register to keep your timeline ad-free for only $19.95.
Twitterrific
Twitterrific is a fun application that lets you both read and publish posts or "tweets" to the Twitter community website. The application's user interface is clean, concise and designed to take up a minimum of real estate on your Mac's desktop.
Seesmic Desktop
Seesmic Desktop: Get Facebook + Twitter on your Desktop, now including comments and likes!
Follow your friends from Facebook and Twitter and update your profile from Seesmic Desktop.
Staying in touch with your friends and building your community has never been that easy.
It is available from today as a free download.
DestroyTwitter
DestroyTwitter is a compact though robust Twitter application built to run on Mac, Windows, and Linux using Adobe AIR. It consists of a series of canvases that constantly update to keep tweets up-to-date using notifications that appear when a new tweet arrives. DestroyTwitter uses a minimal amount of memory compared to its AIR-based alternatives...
Twhirl
twhirl is a desktop client for the Twitter microblogging service. Most of the features available on the Twitter website are accessible through twhirl, too. Plus, a lot of usability enhancements have been added. twhirl is based on the new Adobe AIR platform that allows web development techniques to be used to create desktop applications. It is p...
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